Figure 2.—

epr mutants require DAF-16 for pathogen resistance. epr mutants, ag12 and ag15 (A), ag17 and ag19 (B), were fed with either a vector control or daf-16 RNAi and then transferred to P. aeruginosa PA14 plates. The differences in survival kinetics between wild-type N2 and epr mutants (ag12, ag15, ag17, and ag19) treated with the control RNAi were significant (P < 0.0001). The differences in survival kinetics between the epr mutants treated with control RNAi and daf-16 RNAi were also significant (P < 0.0001). Experiments with ag12 and ag17 were repeated three times and experiments with ag15 and ag19 were repeated twice with similar results.