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. 2008 Feb 15;129(3):253–266. doi: 10.1007/s00418-008-0384-0

Fig. 1.

Fig. 1

Reproduction of the first electron micrograph ever that indicated the existence of lysosomes (arrows), as originally published in 1956 by Novikoff and colleagues. The sample represents a liver fraction that also contains mitochondria (MT) and endoplasmic reticulum (ER). Reproduced from Novikoff et al. (1956)