Skip to main content
. 2008 Feb 19;2008:249849. doi: 10.1155/2008/249849

Table 1.

Statistical analysis of PPAR-α, -β, and -γ immunostaining.

Tumor Blood vessel Stromal tissue
PPAR-α PC (N=156)
Low group N=50) 2.2±0.6 2.0±0.9 2.0±0.9
Middle group N=54) 2.4±0.7 2.3±0.7 1.9±0.6
High group N=52) 2.3±0.7 1.9±0.6 2.0±0.8
PIN (N=15) 1.9±0.6 1.8±0.6 1.7±0.7
BPH (N=20) 2.1±0.6 1.7±0.5 1.7±0.5
NP (N=12) Not present 2.1±0.7 2.2±1.1

PPAR-β PC (N=156)
Low group N=50) 2.0±1.0 1.7±0.7 1.9±0.6
Middle group N=54) 2.3±1.2 1.6±0.7 1.8±0.7
High group N=52) 2.1±1.0 1.7±0.6 1.8±0.9
PIN (N=15) 2.2±0.8 1.8±0.9 1.8±0.7
BPH (N=20) 2.0±0.7 1.9±0.8 1.6±0.7
NP (N=12) Not present 1.9±0.7 1.9±0.8

PPAR-γ PC (N=156)
Low group N=50) 2.6±0.7* 1.8±0.9* 1.8±0.7*
Middle group N=54) 2.7±0.9* 1.8±0.8* 1.9±0.9*
High group N=52) 3.3±1.0* 2.0±0.8* 1.7±0.9*
PIN (N=15) 2.5±0.8* 1.9±0.8* 1.7±0.9*
BPH (N=20) 0.8±0.6 0.6±0.5 0.7±0.5
NP (N=12) Not present 0.5±0.4 0.5±0.3

* Graded 0–4 on the coded sections by two blind observers. 0, no staining; 4+, maximum intensity. Statistical analysis was performed using the ANOVA (p-value). PPAR-α and -β immunostaining were significantly intense in all cases. There were no differnces among PC, PIN, BPH and NP. PPAR-γ immunostainings of tumor were significantly more extensive and intense in PC and in PIN than in tissue of BPH or NP. PPAR-γ staining was high in blood vessels and stromal tissues of PC and PIN, with no significant difference between them. However, the expressions of the PPAR-γ in the blood vessels and stromal tissues from BPH and NP were at the basic level. (* P<.01).