TABLE III.
Summary of the Values of Passive Force, Maximal Active Force, pCa50, ΔpCa50, and nH in Control and sTn-reconstituted PLV in High Passive Force Experiments
SL | Passive force | Maximal force | pCa50 | ΔpCa50 | nH | |
---|---|---|---|---|---|---|
μm | mN/mm2 | mN/mm2 | ||||
Fig. 4 A | ||||||
Control PLV | 1.9 | ∼0 | 57.52 ± 1.92 | 5.56 ± 0.01 | 4.33 ± 0.19 | |
2.3 (high PF) | 14.50 ± 1.04a | 82.23 ± 3.40a | 5.89 ± 0.01a | 0.33 ± 0.01a | 3.77 ± 0.19 | |
PLV (+sTn) | 1.9 | ∼0 | 56.33 ± 1.23 (59.21 ± 3.36) | 5.80 ± 0.03b | 3.76 ± 0.08 | |
2.3 (high PF) | 15.45 ± 0.85a | 68.53 ± 2.34a b | 6.01 ± 0.02a b | 0.21 ± 0.01a | 3.84 ± 0.41 |
Passive force was obtained ∼10 s after increasing SL to 2.3 μm. Numbers in parentheses indicate maximal force values obtained prior to sTn reconstitution (P > 0.05 compared with corresponding values obtained after sTn reconstitution).
P < 0.05 compared with corresponding values obtained in experiments under steady-state passive force (Table II).
P < 0.05 compared with corresponding values for control PLV at high passive force (high PF).