Table 3.
Main studies evaluating the accuracy of pharmacological stress echocardiography in detecting CAV and coronary artery stenosis > 50% in HT recipients (Mod from Thorn EM et al, Heart Fail Clin 2007)
| Authors | N. of pts | Time post-HT (years) | Sensitivity for CV | Specificity for CAV | Sensitivity for cor. stenosis | Sensitivity for cor. stenosis |
| Dobutamine | ||||||
| Akosah KO, 1994 | 41 | 4.8 (0.25–10) | 95% | 50% | 100% | 41% |
| Herregods, J Heart Lung Tr1994 | 28 | 3.2 ± 1.3 | 50% | 71% | - | - |
| Derumeaux G, JACC 1995 | 41 | 3.3 ± 1.7 | 86% | 91% | 100% | 77% |
| Derumeaux G, Arch Mal Coeur 1996 | 64 | 3.3 ± 1.2 | 85% | 97% | 100% | - |
| Akosah KO, JACC 1998 | 22 | 0.17 (0.04–0.3) | 100% | 73% | 100% | 59% |
| Derumeaux G, J Heart Lung Tr 1998 | 37 | 3.1 ± 1.7 4.7 ± 1.8 |
65% 92% |
95% 73% |
- - |
- - |
| Spes GH, Circulation 1999 | 109 | 3.2 ± 3.1 | 72% | 88% | - | - |
| Bacal F, J Heart Lung Tr 2004 | 38 | > 4 | - | - | 64% | 91% |
| Dipyridamole | ||||||
| Ciliberto GR, Eur Heart J 1993 | 80 | 2.3 ± 0.5 | 80% | 85% | 100% | 72% |
| Ciliberto GR. J Heart Lung Tr 2003 | 68 | 2.9 ± 1.9 | 80% | 79% | 100% | 87% |
| Adenosine | ||||||
| Tona F J Heart Lung Tr 2006 | 73 | 8.0 ± 4.5 | 82% | 87% | - | - |
CFR = Coronary flow reserve