TABLE 1.
Clone | Mutationa
|
|||||||
---|---|---|---|---|---|---|---|---|
MA | CA | NC | PR | RT | IN | Vif | Vpr | |
2B7 | nf | V230I | nf | R87G | K102R, D237N | V204I | nf | nf |
2F1 | nf | nf | nf | nf | A62T, D320N | V204I | nf | nf |
2F2 | nf | nf | nf | nf | R83K | V204I, I200T | nf | nf |
2F12 | nf | nf | nf | nf | Y127C, V179I, Q373K | V204I | nf | nf |
3A17 | V35I, E40K | V27I, V230I | R10G | nf | V179I | Q96H, K127E, V204I | R157Gb | V60R |
3B25 | V35I, E40K | V27I, V230I | R10G | nf | V179I | Q96H, K127E, V204I | R157G | V60R |
3C27 | V35I, E40K | V27I, V230I | R10G | nf | V179I | Q96H, K127E, V204I | H43Q, R157G | V60R |
3C32 | V35I, E40K | V27I, V230I | R10G | nf | V179I, A360D | Q96H, K127E, V204I | R157G | V60R |
3C34 | V35I, E40K | V27I, V230I | R10G | nf | V179I, S519K | Q96H, K127E, V204I | V141A | V60R |
3C36 | V35I, E40K, Q55R | V27I, V230I | R10G | nf | V179I | Q96H, K127E, V204I | R157G | V60R |
3C37 | V35I, E40K | V27I, V230I | nf | nf | V179I | Q96H, K127E, V204I | R157G | V60R |
3C82 | V35I, E40K | V27I, V230I | R10G | nf | D67N, V179I | Q96H, K127E, V204I | R157G | V60R |
nf, no mutation found in that region.
R157G is the result of an alanine deletion at position 5059, resulting in a frameshift and an ocher stop codon in the reading frame at amino acid position 158.