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FIG. 2.

FIG. 2.

Infection of cotton rats with cells containing VZV unable to express ORF47 or with parental virus results in similar VZV DNA copy numbers in dorsal root ganglia. Geometric mean copy numbers for animals considered positive (•) are shown. Results for animals with copy numbers below the threshold (10 copies of VZV DNA per 500 ng of ganglia DNA) for reliable detection are indicated by open circles (○). The horizontal bars indicate the geometric mean copy numbers per 500 ng of ganglion DNA for animals who tested positive by PCR. Animals inoculated with cells containing heat-inactivated ROka (HI-ROka) and those receiving either uninfected cells or those not inoculated (Uninfected) had no detectable viral DNA in their ganglia.