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. 2008 Feb 20;3(2):e1656. doi: 10.1371/journal.pone.0001656

Figure 2. Biological significance of the transcriptional system regulators (TSRs).

Figure 2

The most significant biological processes for either side of the respective TSR according to the GO ontology classification are shown for TSR1, TSR2 and TSR50 in panels A, B and C, respectively. Graphs depict the running sum statistics when applying gene set enrichment analysis. The running sum (y-axis) is shown as a function of the index in the list (x-axis) of genes ranked in ascending order according to their factor loadings within TSR. The red vs. green graphs show the biological coherence of opposing regulated gene clusters controlled by TSRs.