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. 2008 Feb 20;3(2):e1656. doi: 10.1371/journal.pone.0001656

Figure 4. Similarities in transcriptional system regulation between human and mouse.

Figure 4

Panels A and B show the results of gene set enrichment analysis for six biological processes for human TSR1 and mouse TSR2, respectively. Graphs show the running sum statistics. The running sum (y-axis) is shown as a function of the index in the list (x-axis) of genes ranked in ascending order according to their factor loadings with a TSR. The red vs. green graphs show the biological coherence of regulated gene clusters controlled by TSRs in both species.