Figure 2.

6C10, but not 3G11, down-modulation on CD4 T cells is correlated with duration of tolerance to Mls-1^a. (Upper) Percent of 6C10⁺ (○) and 3G11^hi (•) CD4 T cells as determined by flow cytometry, on the days indicated after Mls-1^a inoculation (day 120 data not shown). (Lower) Proliferation of purified CD4 T cells in response to Mls-1^a in vitro. Results are expressed as stimulation indices of responses to CBA/J stimulators (day 0 T cells, which incorporated approximately 80,000 cpm) divided by responses to syngeneic CBA/Ca stimulators and represent averages ± SEM of four experiments.