Figure 2.

Antigen presentation by Cat D^−/− APC. Splenocytes from Cat D^+/− (solid bars) or Cat D^−/− mice (shaded bars) were used as APC in assays of antigen recognition by the panel of hybridomas shown in Table 1 in the presence of the indicated concentration of antigen. The epitope recognized by each T cell line is shown under its name. The results shown are representative of at least two experiments in which all the hybridomas specific for the same MHC background were tested with the same combination of Cat D^+/− and Cat D^−/− splenocytes of the appropriate MHC specificity. All values are means of triplicate determinations, and the SD of each value is represented.