Table 1.
Results of the ccanalysis
Residue 18 | cc (μM) | ΔΔG (kcal/mol) |
A | 66 ± 7 | 0.41 |
D | 247 ± 7 | 1.23 |
E | 95 ± 7 | 0.64 |
F | 24 ± 1 | −0.21 |
G | 33 ± 2 | 0.00 |
H | 74 ± 5 | 0.49 |
I | 11 ± 2 | −0.68 |
K | 264 ± 28 | 1.27 |
L | 29 ± 1 | −0.09 |
N | 62 ± 10 | 0.38 |
P | 176 ± 12 | 1.02 |
Q | 31 ± 3 | −0.05 |
R | 48 ± 5 | 0.22 |
S | 187 ± 8 | 1.06 |
T | 40 ± 6 | 0.11 |
V | 32 ± 2 | −0.03 |
W | 26 ± 3 | −0.17 |
Y | 10 ± 1 | −0.75 |
Errors on cc are the standard deviation from four measurements. ΔΔG represents the difference ΔG(residue X) – ΔG(Gly18).