Figure 1.

Calculation of phosphoresidue contact propensities from global and phosphoresidue contact probability distributions. Probability distributions over the total protein surface (upper panels), over the phosphoresidue contact surface (middle panels), and the phosphoresidue contact propensity (lower panels) were calculated for the properties (A) amino acid identity, (B) mean surface curvature, and (C) solvated electrostatic potential. Error bars in lower panels indicate twice the standard deviation of the mean for removing each crystal structure from the data set, one at a time (N = 9). The horizontal lines in the bottom panels indicate the mean phosphoresidue contact propensity, which is always equal to 1.