Figure 1.

The improvement after filtering. The results are (1) 48 out of 60 complexes have I_fact > 1; (2) there are five complexes (1AVW, 1BQL, 1EFU, 1FIN, 1GOT) with I_fact = 1 because FTDock did not generate hits to begin with; (3) there are three complexes for which our filters worsen the results (1FSS, 1IGC, 1MAH) with 1 > I_fact ≥ 0 after filtering; (4) there are four complexes (1EO8, 1L0Y, 1NCA, 1QFU) for which our combined filter failed with I_fact = 0.0 since all of the near-native structures (2, 1, 7, and 5, respectively) were filtered out. After applying only filter II for these seven complexes, I_facts were improved (I_fact > 1.0) (Table 1).