Table 3.

Summary of differences between IDSB-rich and IDSB-poor protein chains

	IDSB-rich	IDSB-poor
Most common header	Toxin	Hydrolase
Most common fold	Knottin	Immunoglobulin-like β-sandwich
Median chain length	42	218
Most common no. of IDSBs	3, normal distribution	1, exponential decay
Most common bonding pattern	Overlapping patterns	Independent patterns
Percent of chains with unbonded cysteines	7%	43%
Most common tail length	N: 2, 1, 0.	N: 2, 3, 5. C: 1, 2, 0.
	C: 0, 1, 2.	Second mode near 21 residues.
No. of chains	313	967