Table 1.
YGG-3X and coil reference peptides: Sequence and 13C′ label positions (underlined)
All 13C′ positions studied | |
YGG-3A | Ac-YGGKAAAAKAAAAKAAAAK-NH2 |
YGG-3V | Ac-YGGKAVAAKAVAAKAVAAK-NH2 |
Helix Nos.a | 8 7 6 5 4 3 2 1 1 2 3 4 5 6 7 8 |
Specific isotopomers of YGG-3V | |
3V(10,12) | Ac- YGGKAVAAKAVAAKAVAAK-NH2 |
3V(7,12) | Ac- YGGKAVAAKAVAAKAVAAK-NH2 |
3V(8,12,13) | Ac- YGGKAVAAKAVAAKAVAAK-NH2 |
Coil reference peptides | |
Coil-A | Ac- GKAAAKG- NH2 |
Coil-V | Ac- GKAVAAK- NH2 |
a Helix positions are numbered from the center of the helix, which spans from K4 to K19 under conditions favoring helix formation; the central residues are numbered as −1 and +1, with larger negative and positive numbers on progressing to the N and C terminus, respectively.