Table 5.
Relationship between age, body mass index, minute ventilation (Ve) and change in pulmonary function parameters after ozone exposure for subset of subjects having Ve measures during exposure. Beta is the coefficient for the associated predictor in the regression model and the square of the regression coefficient, R2, applies to the regression model that includes both predictors, age and BMI.
All (n = 127) |
Males (n = 80) |
Females (n = 47) |
|||||
---|---|---|---|---|---|---|---|
Δ (%) | Predictor | Beta | p-value | Beta | p-value | Beta | p-value |
FEV1 | Age | 0.416 | 0.08 | 0.011 | 0.97 | 0.749 | 0.035 |
BMI | −0.797 | 0.019 | −0.313 | 0.54 | −1.116 | 0.020 | |
Ve | 0.181 | 0.38 | −0.222 | 0.60 | 0.704 | 0.11 | |
R2 | 0.059 | 0.018 | 0.222 | ||||
FVC | Age | 0.338 | 0.08 | 0.016 | 0.09 | 0.602 | 0.044 |
BMI | −0.635 | 0.020 | −0.244 | 0.54 | −0.814 | 0.042 | |
Ve | 0.192 | 0.24 | −0.267 | 0.42 | 0.518 | 0.17 | |
R2 | 0.060 | 0.028 | 0.190 | ||||
FEF25-75a | Age | 0.388 | 0.28 | −0.194 | 0.70 | 0.789 | 0.11 |
BMI | −1.253 | 0.013 | −0.198 | 0.80 | −2.108 | 0.002 | |
Ve | 0.218 | 0.48 | −0.429 | 0.51 | 1.061 | 0.09 | |
R2 | 0.054 | 0.015 | 0.256 | ||||
FEV1/FVC | Age | 0.120 | 0.36 | 0.020 | 0.92 | 0.194 | 0.29 |
BMI | −0.241 | 0.19 | −0.102 | 0.72 | −0.426 | 0.09 | |
Ve | 0.010 | 0.93 | 0.031 | 0.90 | 0.266 | 0.25 | |
R2 | 0.021 | 0.002 | 0.103 | ||||
FEF25- 75/FVCa |
Age | 0.155 | 0.63 | −0.198 | 0.67 | 0.345 | 0.43 |
BMI | −0.823 | 0.07 | 0.042 | 0.95 | −1.645 | 0.007 | |
Ve | 0.054 | 0.85 | −0.288 | 0.62 | 0.734 | 0.19 | |
R2 | 0.030 | 0.006 | 0.173 |