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. 2008 Jan 4;82(1):57–72. doi: 10.1016/j.ajhg.2007.09.012

Table 5.

The Parameters Used for Estimation of the s Given the Age by Means of the General Selection Formula

Populationa Allele Ages of the Allele (g ± SD)b Current Allele Frequency (p)c Selection Coefficient (s)
1. Saudi Arabians G−13915 163 (±81) 0.57 0.0507 (0.0337–0.1007)
2. Moroccans G−13915 47 (±24) 0.08 0.0968 (0.0650–0.1978)
T−13910 82 (±41) 0.21 0.0713 (0.0479–0.1426)
3. Saharawi G−13915 135 (±95) 0.18 0.0415 (0.0244–0.1402)
T−13910 149 (±74) 0.26 0.0417 (0.0277–0.0828)
4. Arabs G−13915 35 (±17) 0.10 0.1377 (0.0909–0.2677)
T−13910 39 (±28) 0.10 0.1236 (0.0719–0.4381)
5. Utahans T−13910 223 (±25) 0.74 0.0484 (0.0437–0.0545)
6. Fulani T−13910 245 (±28) 0.48 0.0318 (0.0286–0.0358)
7. Finns, East T−13910 217 (±34) 0.54 0.0380 (0.0328–0.0450)
8. Finns, West T−13910 208 (±23) 0.62 0.0434 (0.0391–0.0488)
9. Basques T−13910 208 (±23) 0.66 0.0457 (0.0412–0.0514)
a

In populations 1–4, the age estimates were based on the sequence of intron 13 of MCM6 gene (3218 bp), whereas for populations 5–9, the age estimates were based on typing of 9 SNP over a 30 kb region as shown previously.

b

Age estimates were based on Rho statistic (± SD) as shown in Table 2.

c

In all calculations, the initial gene frequency (p0) was 0.001.