Table 5.
Populationa | Allele | Ages of the Allele (g ± SD)b | Current Allele Frequency (p)c | Selection Coefficient (s) |
---|---|---|---|---|
1. Saudi Arabians | G−13915 | 163 (±81) | 0.57 | 0.0507 (0.0337–0.1007) |
2. Moroccans | G−13915 | 47 (±24) | 0.08 | 0.0968 (0.0650–0.1978) |
T−13910 | 82 (±41) | 0.21 | 0.0713 (0.0479–0.1426) | |
3. Saharawi | G−13915 | 135 (±95) | 0.18 | 0.0415 (0.0244–0.1402) |
T−13910 | 149 (±74) | 0.26 | 0.0417 (0.0277–0.0828) | |
4. Arabs | G−13915 | 35 (±17) | 0.10 | 0.1377 (0.0909–0.2677) |
T−13910 | 39 (±28) | 0.10 | 0.1236 (0.0719–0.4381) | |
5. Utahans | T−13910 | 223 (±25) | 0.74 | 0.0484 (0.0437–0.0545) |
6. Fulani | T−13910 | 245 (±28) | 0.48 | 0.0318 (0.0286–0.0358) |
7. Finns, East | T−13910 | 217 (±34) | 0.54 | 0.0380 (0.0328–0.0450) |
8. Finns, West | T−13910 | 208 (±23) | 0.62 | 0.0434 (0.0391–0.0488) |
9. Basques | T−13910 | 208 (±23) | 0.66 | 0.0457 (0.0412–0.0514) |
In populations 1–4, the age estimates were based on the sequence of intron 13 of MCM6 gene (3218 bp), whereas for populations 5–9, the age estimates were based on typing of 9 SNP over a 30 kb region as shown previously.
Age estimates were based on Rho statistic (± SD) as shown in Table 2.
In all calculations, the initial gene frequency (p0) was 0.001.