Figure 3.

Distribution of the mtDNA Deletion Breakpoints Detected from Substantia Nigra Neurons

This graph shows the distribution of the detected mtDNA deletion breakpoints within the genome. It is clear that although the 5′ breakpoints have a complicated distribution, the 3′ breakpoints form three clusters. The breakpoint locations of the deletions from the PD patients are shown in black, those from the aged neurons are in gray, and those from the patient with multiple mtDNA deletions are hatched. MDP indicates a multiple-deletion patient.