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Post treatment prophylaxis following a slowly eliminated antimalarial such as chloroquine or piperaquine in a high transmission setting (left figure) where the EIR is 1000/year and in a low transmission setting where the EIR is 1/year. The drug concentrations are shown in red and the vertical bars represent cumulative incidence of reinfection; t20 and t50 are the times to reach a 20% and 50% cumulative incidence of reinfection.
