Table 1.
Baseline demographic and clinical features, and treatment retention rates, for cocaine dependent patients (N = 167) with major depression, ADHD, or no psychiatric comorbidity, randomized to the placebo arms of one of three clinical trials.a
| Baseline Variable | No Comorbidity (gabapentin trial) (n=48) | ADHD (methylphenidate trial) (n=53) | Major Depression (venlafaxine trial) (n = 66) | X or F b (d.f.) | P |
|---|---|---|---|---|---|
| Demographics | |||||
| Age (years) | 39 (8) | 37 (6) | 38 (8) | 0.85 (2,163) | 0.43 |
| Male | 39 (89%) | 44 (83%) | 48 (73%) | 2.16 (2) | 0.34 |
| Race: Caucasian | 14 (29%) | 31 (58%) | 22 (33%) | 18.11 (6) | .006 |
| Hispanic | 7 (15%) | 8 (15%) | 19 (29%) | ||
| African-American | 24 (50%) | 11 (21%) | 19 (29%) | ||
| Other | 3 (6%) | 3 (6%) | 6 (9%) | ||
| Education (College/post-Grad) | 24 (63%) | 29 (55%) | 30 (48%) | 2.36 (2) | 0.31 |
| Currently Employed | 28 (82%) | 38 (72%) | 41 (68%) | 4.20 (4) | 0.38 |
| Currently Married | 12 (31%) | 14 (26%) | 20 (31%) | 0.84 (4) | 0.93 |
| Income Under 25 K | 15 (47%) | 22 (43%) | 24 (44%) | 7.11 (4) | 0.13 |
| 25K – 50 K | 9 (28%) | 19 (37%) | 27 (49%) | ||
| Over 50 K | 8 (25%) | 10 (20%) | 4 (7%) | ||
| SCID | |||||
| Current MJ A/D | 7 (23%) | 15 (28%) | 6 (13%) | 3.24 (2) | 0.20 |
| Current Alcohol A/D | 7 (23%) | 24 (45%) | 14 (32%) | 4.42 (2) | 0.11 |
| Baseline Cocaine use | |||||
| Days of cocaine use (in last 30 days) | 14 (8) | 13 (8) | 15 (9) | 0.99 (2,161) | 0.38 |
| Total $ amount spent on cocaine per week (last 30 days) | $359 ($341) | $291 ($256) | $316 ($368) | 0.52 (2,154) | 0.60 |
| Retention in Treatment | |||||
| Weeks in Treatment | 8 (4) | 8 (5) | 9 (4) | 0.94 (2) c | 0.63 |
| Completed treatment(12 weeks) | 20 (42%) | 24 (45%) | 31 (47%) | 0.32(2) | 0.85 |
a
Values in the table are N (%) for categorical variables, or Mean (SD) for continuous variables.
b
Value of chi-square or F statistic, depending of whether the variable is categorical or continuous.
c
Log-Rank test.