Figure 3.

Weblogo representation of the conservation pattern of residues in each group and for the entire protein family. The previously described main CLE motif of 12 amino acid length is marked with a black frame. Group specific residues are marked in black in the various groups. Invariant residues are marked in black in the bottommost logo. Conserved residues are marked grey. The size of the letter symbolizes the frequency of that residue in the group and at that position. A secondary motif was identified at around 50 amino acids upstream of the primary CLE motif in groups 1, 2, 8 and 13. Extensions of the motif are recognizable at both the C- and N-terminus. Bracketed figures indicate the number of sequences assigned to the respective group.