Table 1.

Description of study sites and intervention implementation in four sites evaluating home management of malaria with artemisinin combination therapy

	Ejisu – Juaben District, Ghana	Ho District, Ghana	Badeku and Ojoku/Ajia Districts, Nigeria	Bugiri and Iganga Districts, Uganda
Population characteristics	35 rural communities Population c. 38,000 Perennial malaria transmission	49 urban & rural communities Population c. 42,000 Perennial malaria transmission	40 rural communities Population 43,000 Perennial, hyperendemic malaria transmission	56 rural communities Population c. 60,000 Perennial, hyperendemic transmission
Community medicine distributors	54 (51 male) trusted members of community (farmers, teachers, drug sellers), chosen by the community	76 (48 male) trusted members of community (farmers, teachers, drug sellers), chosen by the community	60 (4 male) including drug sellers, health workers and mothers chosen by the communities	118 (62 male) pre-existing cadre of CMDs (chosen by the community)
	5 days of training	2 days of training	2 days of training	2 days of training
	Provided with bicycles, boots & $3.50 monthly	Provided with T-shirts, watches, raincoats, torches & US$8 quarterly	Received commission of 20–30 US cents per pack distributed. Provided with T-shirts, transport reimbursement, Festivity gift, and certificates.	Transport refund of USD 1.16 per meeting. T-shirts, baseball caps, certificates
	Bimonthly supervision by research staff; Monthly supervision by community Health Officers	Monthly supervision by health staff and quarterly meetings	Monthly supervision by research staff	Monthly supervision by health staff
	CMDs were not obliged to follow up caregivers. However, some of them followed up and some gave drugs under direct observation.		No active follow-up of caregivers by CMDs.	Program ran within existing home management system. CMDs actively followed up treated children to establish treatment outcome
Drugs and dosing schedule	Artesunate+Amodiaquine (ASAQ) once daily for 3 days 2 types of blister pack, for children < 1 year and children 1 year and above		Artemether-lumefantrine (Coartem®) twice daily for 3 days 2 types of blister pack, for children < 3 years and children 3 years and above
	10 US cents for <1 year 20 US cents for 1 year and above		20 US cents for < 3 years 30 US cents for 3 years and above Charged for first 6 months only, thereafter free	Free