Table 1. Metaphase cells with one or more abnormal chromosomes.
Animal status and age | Total number of abnormal chromosomes (abnormal cells/total cells in metaphase) | Types of aberrations |
---|---|---|
Eight-week-old control |
15 (2/13) |
Small marker chromosomes |
Eight-week-old irradiation |
27 (4/15) |
Chromatid break; trisomy 8; trisomy 18; + marker chromosomes |
26-month-old control* |
0 (0/5) |
|
26-month-old radiation* | 30 (3/10) | + small markers; chromatin unraveling |
The asterisk indicates that a set of 26-month-old animals has been added from a separate but same procedure X-ray study to increase the total number of cells examined for post X-ray chromosomal abnormalities. The first number indicates the total number of abnormal chromosomes found. The numbers inside the parentheses indicate the fraction of abnormal cells (some with several abnormal chromosomes) over the total cells that were present in a complete metaphase spread condition.