TABLE 1.
Parameters used in the model
| Symbol | Description |
|---|---|
| R*n | Activated rhodopsin in state n |
| R0 | Deactivated rhodopsin |
| T | Transducin |
| T* | Activated transducin |
| PDE | Phosphodiesterase |
| PDE* | Activated PDE |
| Np | Number of rhodopsin phosphorylation sites |
| λn | Phosphorylation rate in state n |
| μn | Arrestin binding rate in state n |
| kact(n) | Transducin activation rate in state n |
| k3 | PDE activation rate |
| k4 | PDE* deactivation rate |
| Rτ | Mean/SD ratio of rhodopsin lifetime |
| RPs | Steady-state mean/SD ratio of PDE* |
| RP(t) | Time-dependent mean/SD ratio of PDE* |
 |
Maximum number of PDE* |