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. 2007 Dec 7;94(6):2053–2064. doi: 10.1529/biophysj.107.113977

TABLE 1.

Parameter values used in the modified cross-bridge model

Parameter values determined by fit to the experimental data
Airway model
parameters Values in our model 95% range
k1a  0.5962 s−1 [0.34, 0.88]
k1b  1.35 μM [1.1731, 1.5272]
kon1  0.000125 [0.0001, 0.0002]
kon2  0.8988 μM [0.7551, 1.0377]
koff1  0.4629 [0.3992, 0.5132]
koff2  20.035 [17.7670, 21.7317]
τp  156.9 s [132.8425, 171.6565]
Inline graphic  242.14 s−1 [164.6281, 337.2143]
g1  0.1211 s−1 [0.1123, 0.1281]
Arteriole model
parameters Values in our model 95% range
kon2  0.000174 μM [0.0001, 0.0006]
koff2  120.84 [107.6515, 136.7734]
τp  564.67 s [533.6403, 595.8495]
Inline graphic  76.23 s−1 [73.6590, 78.8780]
g1  0.03 s−1 [0.0291, 0.0311]
k1b  0.7 μM From Geguchadze et al. (31) and Fajmut et al. (32)
Parameter values taken from Mijailovich et al. (8)
fp1 0.88 s−1 gp1 0.22 s−1
Other parameter values
β 2 γ 44.87

The values either were determined by fitting to data or were taken from Mijailovich et al. (8). The 95% confidence intervals are obtained from MCMC (see Appendix).