TABLE 3.
GFR | TCR | |
---|---|---|
Parameter | ||
rtotal | 0.2 | 0.2 |
c1 | 0.05 | 0/0.05 |
c2 | 1 | 1 |
c–2 | 0.1 | 0.1 |
c3 | 1 | 1 |
c–3 | 0.01 | 0.01 |
c4 | 1 | 0 |
c–4 | 0.01 | 0 |
c5 | 1 | 1 |
c–5 | 1 | 1 |
c6 | 1 | 0 |
c–6 | 1 | 0 |
c7 | = k3 | = k3 |
c–7 | = p1 | = p1 |
c8 | = k3 | = k3 |
c–8 | = p1 | = p1 |
c9 | 1 | 1 |
c–9 | 0.01 | 0.01 |
kp | 0.1 | 0.1/0.6 |
k–Cbp | 0.02 | 0.01 |
k+Cbp | 0 | 0.005 |
kSHP | NA | 2 |
k2;min | 0.3 | 0.3 |
k2;max | 0.6 | 0.6 |
ρRsrc | 1 | 1 |
Initial conditions | ||
Variable* | ||
SHP | 0 | 1 |
Cbp/PAGpY317 | 0.009 | 0.045 |
Cbp/PAG:Csk | 0.172 | 0.869 |
PTPαpY798 | 0.198 | 0.198 |
Parameters are in arbitrary, dimensionless units (see Methods).
Zero for all variables other than those noted in Table 3.