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. 2008 Jan 30;9:16. doi: 10.1186/1471-2202-9-16

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Copyright © 2008 Rostron et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Photomicrographs illustrating the extent of ChAT positive neuronal loss in the region of the nucleus basalis magnocellularis. The two panels show: A – ChAT positive neurons in a control animal (infusion of Dulbeccos saline), B – Extensive loss of ChAT positive neurons in the same location in an animal who received bilateral infusions of 192 IgG Saporin. Abbreviations: HDB = Horizontal diagonal band of Broca, MCPo = Magnocellular preoptic nucleus, SIB = Substantia innominata basal part.