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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: Microvasc Res. 2007 Jul 6;75(1):53–58. doi: 10.1016/j.mvr.2007.06.007

Figure 4.

Figure 4

Functional assessment of MIP-2 treatment on aortic endothelial cells showing chemotaxis (# of migrated aortic endothelial cells) and with inhibitor of Rho kinase (Y27632). Aortic endothelial cells were incubated for 30 min with the Rho kinase inhibitor-Y27632 (5 μM) or vehicle control (PBS) followed by a 2 hr treatment with MIP-2 (10 ng/ml). A significant increase in the number of migrated cells was apparent after MIP-2 treatment (n=3-4 experiments /group; * indicates p < 0.05). However, there was no change in the number of migrated cells after MIP-2 if the cells were pretreated with the Rho kinase inhibitor (p > 0.05 from vehicle control without MIP-2).