FIGURE 1.

Number of major histocompatibility complex class II+ Langerhans cells (LCs) in the cornea 1 week following cauterization, based on treatment modality. Topical application of IL-1Ra (P = .01), sTNFR (P = .04), sTNFR + IL-1Ra (P = .01), and Pred (P = .001) leads to significant reduction in number of infiltrating LCs as compared to vehicle-treated controls. Topical Pred alone leads to a suppression level significantly greater than that observed for sTNFR (P = .03) but not compared to IL-1Ra (P = .4). Bars represent standard error of the mean.