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Keratocyte density in normal (unoperated) corneas, clear penetrating grafts, and grafts with late endothelial failure (LEF) is shown as a function of stromal depth. Keratocyte densities in all layers of the stroma after penetrating keratoplasty (clear grafts or grafts with LEF) were significantly lower than in normal corneas (P < .01). No differences were detectable between clear grafts and grafts with LEF.
