TABLE 3.
EFFECT OF USING DIFFERENT NUMERIC THRESHOLDS (“CUTOFF POINTS”) ON THE AGREEMENT OR DISAGREEMENT OF THE COMPUTER PROGRAM (ROPtool) WITH EXPERT CONSENSUS*
| EXPERT CONSENSUS | |||
|---|---|---|---|
| Plus | Not Plus | ||
| ROPtool with cutoff of 8 tortuosity units | Plus | 36 | 21 |
| Not Plus | 1 | 127 | |
| ROPtool with cutoff of 9 tortuosity units (a priori) | Plus | 36 | 9 |
| Not Plus | 1 | 139 | |
| ROPtool with cutoff of 10 tortuosity units | Plus | 35 | 6 |
| Not Plus | 2 | 142 | |
| ROPtool with cutoff of 11 tortuosity units | Plus | 33 | 4 |
| Not Plus | 4 | 144 | |
| ROPtool with cutoff of 12 tortuosity units | Plus | 30 | 4 |
| Not Plus | 7 | 144 | |
| ROPtool with cutoff of 13 tortuosity units | Plus | 28 | 2 |
| Not Plus | 9 | 146 | |
| ROPtool with cutoff of 15 tortuosity units | Plus | 30 | 0 |
| Not Plus | 14 | 148 | |
*
Note that as the cutoff point increases, sensitivity decreases (more false-negatives) and specificity increases (fewer-false positives).