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. 2007 Dec;105:594–615.

TABLE 5.

MEAN QUADRANT TORTUOSITY MEASURED BY COMPUTER PROGRAM (ROPtool) FOR EACH LEVEL OF MEAN EXPERT GRADE

MEAN EXPERT GRADE* MEAN QUADRANT TORTUOSITY (95% CI) P VALUE
 0.0 4.49 (4.34–4.64) <.001
 0.3 6.20 (5.84–6.56) <.001
 0.7 8.56 (7.59–9.52) .2
 1.0 9.67 (8.44–10.90) .05
 1.3 11.49 (10.16–12.83) <.001
 1.7 16.03 (14.01–18.05) .002
 2.0 21.30 (18.91–23.69)
Normal (0.0–0.3) 4.80 (4.65–4.95) <.001
Pre-plus (0.7–1.3) 9.88 (9.17–10.59) <.001
Plus (1.7–2.0) 19.06 (17.36–20.76)

CI, confidence interval.

*

Three experts graded the tortuosity of each quadrant as 2 = plus disease, 1 = pre-plus disease, and 0 = normal.