FIGURE 28.

Horizontal axonal connections between same- and opposite-eye ocular dominance columns caused by correlated and decorrelated binocular input during an early critical period. Correlated activity (“cells that fire together, wire together”) stabilizes immature binocular connections, resulting in equivalent numbers of monocular/same-eye and binocular/opposite-eye connections. Decorrelated activity punishes immature binocular connections (“cells that fire apart, depart”) resulting in a paucity of binocular, but retained monocular connections.