Table 1. Baseline demographic and clinical characteristics of the Day 3 per-protocol population.
| Characteristic | CPG–DDS | +artesunate 1 mg/kg | +artesunate 2 mg/kg | +artesunate 4 mg/kg |
| Adults | N = 23 | N = 22 | N = 22 | N = 18 |
| Median age, years (range) | 27.0 (18−55) | 25.0 (18−50) | 27.0 (21−59) | 28.0 (18−58) |
| Male sex, n (%) | 12 (52.2) | 12 (54.5) | 13 (59.1) | 12 (66.7) |
| Median weight, kg (range) | 53.8 (44.5−66.0) | 56.3 (42.0−81.0) | 53.5 (44.0−76.0) | 54.9 (42.5−76.0) |
| Median pre-dose parasitemia, µL−1 (inter-quartile range) | 26912 (14854:44120) | 16279 (10451:35707) | 22828 (15366:30121) | 22527 (13537:49021) |
| Children | N = 22 | N = 25 | N = 23 | N = 22 |
| Median age, months (range) | 29.0 (14−112) | 46.0 (13−116) | 36.0 (13−118) | 40.5 (15−121) |
| Male sex, n (%) | 13 (59.1) | 13 (52.0) | 17 (73.9) | 12 (54.5) |
| Median weight, kg (range) | 10.9 (7.9−29.8) | 13.4 (7.4−25.6) | 12.8 (8.2−35.8) | 12.4 (7.3−26.2) |
| Median pre-dose parasitemia, µL−1 (inter-quartile range) | 44973 (34596:56027) | 37730 (30757:50656) | 45880 (30800:59307) | 39972 (24480:56022) |
NB: All patients were black African.