Table 1.
Clinical and demographic characteristics of the study groups
| Nyanza Provincial General Hospital (NPGH)
|
Kisii District Hospital (KDH)
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Severe Anemia
|
Cerebral Malaria
|
Cerebral Malaria
|
|||||||
| Variable | Cases (N = 75) | Controls (N = 74) | P | Cases (N = 8) | Controls (N = 15) | P | Cases (N = 24) | Controls (N = 37) | P |
| Mean age (SD) in months | 16.9 (13.7) | 16.8 (13.3) | NSb | 35.9 (15.9) | 35.7 (15.7) | NS | 32.2 (20.4) | 32.7 (16.8) | NS |
| No. Females (%) | 34 (45.3) | 33 (44.6) | NS | 4 (50) | 8 (53.3) | NS | 12 (50) | 19 (51.4) | NS |
| Mean Haemoglobin (SD) g/dL | 4.7 (0.9) | 8.7 (1.5) | NAc | 8.6 (1.6) | 9.1 (1.3) | 0.45 | 9.2 (1.8) | 9.6 (1.7) | 0.45 |
| %Corrected Reticulocyte (SD)d | 1.5 (1.6) | 1.4 (1.9) | NS | 1.6 (1.6) | 1.4 (1.4) | NS | 1.5 (1.4) | 1.5 (1.8) | NS |
| Mean # Parasites/μL ×10−3 (SD) | 71.1 (27.1) | 50.4 (32.1) | 0.12 | 49.5 (46.8) | 49.2 (24.6) | 0.88 | 67.7 (76.4) | 40.4 (60.9) | 0.10 |
| Home District (%) | |||||||||
| Kisumu | 30 (40.0) | 38 (51.3) | 4 (50) | 6 (40) | 0 | 0 | |||
| Bondo | 7 (9.3) | 4 (5.4) | 0 | 4 (26.7) | 0 | 0 | |||
| Nyando | 15 (20.0) | 5 (6.7) | 0 | 2 (13.3) | 0 | 0 | |||
| Siaya | 12 (16.0) | 11 (14.9) | 1 (12.5) | 1 (6.7) | 0 | 0 | |||
| Vihiga | 3 (4.0) | 3 (4.1) | 1 (12.5) | 1 (6.7) | 0 | 0 | |||
| Rachuonyo | 2 (2.7) | 4 (5.4) | 0 | 0 | 0 | 0 | |||
| Kisii | 0 | 0 | 0 | 0 | 6 (25) | 10 (27.0) | |||
| Kisii Central | 0 | 0 | 0 | 0 | 10 (41.7) | 24 (64.9) | |||
| Gucha | 0 | 0 | 0 | 0 | 3 (12.5) | 2 (5.4) | |||
| Otherse | 6 (8.0) | 9 (12.2) | 2 (25) | 1 (6.7) | 5 (20.8) | 1 (2.7) | |||
| Ethnic group (%) | |||||||||
| Luo | 66 (88.0) | 65 (87.8) | 7 (87.5) | 14 (93.3) | 1 (4.2) | 1 (2.7) | |||
| Luhya | 6 (8.0) | 9 (12.2) | 1 (12.5) | 1 (6.7) | 2 (8.3) | 0 | |||
| Abagusii | 0 | 0 | 0 | 0 | 21 (87.5) | 36 (97.3) | |||
| Othersf | 3 (4.0) | 0 | 0 | 0 | 0 | 0 | |||
a
All P values were obtained using paired t-test.
b
NS = Not Significant.
c
NA = Not applicable.
d
Corrected % reticulocyte was calculated as = % reticulocyte × (Subject Hct/Normal Hct) where normal Hct was 35% for age 0 to ≤6 months, 33% for age >6 to ≤12 months, 30% for age >12 to ≤24 months, 33% for age >24 to ≤ 48 months, and 36% for age >48 months.