Table 4.
Gene ontologies for up-regulated processes in BCs versus leukocytes
| Gene category | List hits | EASE score |
| Development (developmental) | 178 | 6.39E-09 |
| Morphogenesis (developmental) | 116 | 1.98E-08 |
| Organogenesis (developmental) | 105 | 5.04E-08 |
| Cellular process | 482 | 6.48E-08 |
| Cell communication | 257 | 4.78E-07 |
| Cell adhesion | 68 | 4.05E-06 |
| Skeletal development (developmental) | 25 | 4.44E-06 |
| Cell-cell signaling | 64 | 4.86E-06 |
| Ion transport | 62 | 8.10E-05 |
| Circulation | 20 | 9.47E-05 |
| Metal ion transport | 38 | 2.53E-04 |
| Cartilage condensation | 6 | 3.56E-04 |
| Cation transport | 46 | 5.97E-04 |
| G-protein coupled receptor protein signaling pathway | 61 | 8.03E-04 |
| Regulation of blood pressure | 9 | 9.06E-04 |
| Neurogenesis (neuronal) | 46 | 1.17E-03 |
| Second-messenger-mediated signaling | 19 | 1.32E-03 |
| Cell surface receptor linked signal transduction | 93 | 1.52E-03 |
| Bone remodeling | 9 | 2.01E-03 |
| Ossification | 9 | 2.01E-03 |
| Cell homeostasis | 15 | 2.07E-03 |
| Cell ion homeostasis | 14 | 2.27E-03 |
| Ion homeostasis | 14 | 2.27E-03 |
| Transition metal ion transport | 9 | 2.40E-03 |
| Transport | 151 | 2.97E-03 |
| Homeostasis | 15 | 3.10E-03 |
| Transition metal ion homeostasis | 7 | 3.37E-03 |
| Receptor mediated endocytosis | 7 | 4.20E-03 |
| Metal ion homeostasis | 11 | 4.48E-03 |
| Homophilic cell adhesion | 15 | 5.91E-03 |
| Di-, tri-valent inorganic cation homeostasis | 10 | 6.86E-03 |
| Gas transport (erythrocytic) | 5 | 7.51E-03 |
| Oxygen transport (erythrocytic) | 5 | 7.51E-03 |
| Cation homeostasis | 12 | 8.76E-03 |
| Angiogenesis (blood vessel development) | 8 | 1.10E-02 |
| Cyclic-nucleotide-mediated signaling | 15 | 1.13E-02 |
| Transmission of nerve impulse (neurophysiology) | 27 | 1.16E-02 |
| Monovalent inorganic cation transport | 28 | 1.19E-02 |
| Di-, tri-valent inorganic cation transport | 14 | 1.42E-02 |
| Enzyme linked receptor protein signaling pathway | 21 | 1.42E-02 |
| Synaptic transmission (neurophysiology) | 26 | 1.42E-02 |
| Blood vessel development (blood vessel development) | 8 | 1.44E-02 |
| Iron ion homeostasis | 5 | 1.64E-02 |
| Blood coagulation (coagulation) | 13 | 1.80E-02 |
| Tyrosine kinase signaling pathway | 15 | 1.99E-02 |
| Signal transduction | 177 | 2.18E-02 |
| Potassium ion transport | 17 | 2.47E-02 |
| Hemostasis | 13 | 2.77E-02 |
| Pregnancy | 8 | 2.89E-02 |
| Axon guidance (neurophysiology) | 6 | 4.00E-02 |
When these genes were clustered based on their GO, we identified processes involved in development, nervous system development, blood vessel development and angiogenesis, and erythrocytes.