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. 2007 Nov 13;8(11):R240. doi: 10.1186/gb-2007-8-11-r240

Table 6.

Gene ontologies for up-regulated processes in BCs versus stromal cells

Gene category List hits EASE score
Cell communication 328 7.47E-07
Cellular process 617 1.25E-06
Cell-cell signaling 79 4.71E-06
Response to external stimulus (lymphocytic) 160 1.38E-05
Ion transport 74 4.07E-04
Response to abiotic stimulus (lymphocytic) 72 4.61E-04
Transport 199 8.97E-04
Cation transport 56 1.08E-03
Defense response (lymphocytic) 95 1.09E-03
Metal ion transport 44 1.30E-03
Response to biotic stimulus (lymphocytic) 101 1.35E-03
Development (developmental) 192 1.55E-03
Intracellular receptor-mediated signaling pathway 8 1.72E-03
Organogenesis (developmental) 108 1.98E-03
Cell adhesion 72 2.17E-03
Morphogenesis (developmental) 118 2.98E-03
Synaptic transmission (neurophysiology) 35 3.04E-03
Signal transduction 238 4.29E-03
Transmission of nerve impulse (neurophysiology) 35 5.07E-03
Regulation of blood pressure 9 5.42E-03
Monovalent inorganic cation transport 36 6.29E-03
Steroid hormone receptor signaling pathway 7 6.65E-03
Homeostasis 17 6.77E-03
Cell surface receptor linked signal transduction 113 8.56E-03
Perception of abiotic stimulus (lymphocytic) 39 1.09E-02
Hemostasis 17 1.10E-02
Second-messenger-mediated signaling 20 1.18E-02
Potassium ion transport 22 1.19E-02
Cyclic-nucleotide-mediated signaling 18 1.24E-02
Blood coagulation (coagulation) 16 1.39E-02
Response to chemical substance (lymphocytic) 31 1.45E-02
Heme biosynthesis (erythrocytic) 5 1.48E-02
Gas transport (erythrocytic) 5 2.00E-02
Oxygen transport (erythrocytic) 5 2.00E-02
Neurogenesis (neuronal) 51 2.02E-02
Cell homeostasis 15 2.31E-02
Perception of external stimulus (lymphocytic) 41 2.41E-02
Estrogen receptor signaling pathway 4 2.48E-02
Heme metabolism (erythrocytic) 5 2.61E-02
Homophilic cell adhesion 16 2.74E-02
Pigment biosynthesis (erythrocytic) 6 2.84E-02
Circulation (erythrocytic) 17 2.94E-02
Olfaction 9 3.02E-02
Response to pest/pathogen/parasite (lymphocytic) 52 3.19E-02
Acute-phase response (coagulation) 6 3.43E-02
Skeletal development 19 3.72E-02
Sensory perception 37 3.86E-02
Disaccharide metabolism 3 3.86E-02
Enzyme linked receptor protein signaling pathway 24 3.96E-02
Heart development (heart development) 6 4.09E-02

This comparison identified the most number of genes and had the most diverse gene ontologies.