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. Author manuscript; available in PMC: 2009 Jan 29.
Published in final edited form as: Brain Res. 2007 Nov 28;1191:180–191. doi: 10.1016/j.brainres.2007.11.034

Figure 1. Decreased opioid receptor mRNA expression in TMEV-infected mice.

Figure 1

(A) Quantitative real-time PCR was utilized to analyze spinal cord opioid receptor mRNA expression in TMEV-infected and uninfected control mice. TMEV infection caused a significant decrease in mu opioid receptor mRNA expression in male and female mice compared to uninfected controls (*p<0.05). (B) TMEV-infected male and female mice had significantly decreased delta opioid receptor mRNA expression compared to uninfected controls (* p<0.05). TMEV-infected male mice had significantly decreased delta opioid receptor mRNA expression at days 90 and 150 PI († p<0.05) compared to TMEV-infected female mice. (C) Kappa opioid receptor mRNA expression was significantly decreased in TMEV infected male and female mice compared to uninfected controls (* p<0.05). TMEV-infected male mice had significantly decreased delta opioid receptor mRNA expression at day 150 PI († p<0.05) compared to TMEV-infected female mice. Results are displayed as the mean ± SEM (n = 5). Significant differences were determined using a two-way ANOVA followed by Bonferroni’s post hoc test.

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