Table 2.
Bacterial strains | Challenge dose | Number of animals | Bacteraemiaa | Pb |
---|---|---|---|---|
MC58 wild type | 3.2 × 107 | 40 | 8.3 × 105 | |
mapAKO | 3.6 × 107 | 40 | 3.9 × 102 | 2.4 × 10−7 |
galMKO | 3.7 × 107 | 40 | 8.9 × 103 | 2.0 × 10−3 |
Values are geometric means of the bacterial cfu ml−1 measured in the blood of each animal.
The significance of difference in the level of bacteraemia was evaluated by two-tailed t-test.
Six-week-old BALB/c mice, 10 mice per group, were infected with the indicated amount of bacteria in four independent experiments. Bacteraemia was measured 18 h after intraperitoneal challenge.