Table 3.
Mouse infection assay with MC58 wild-type and the complemented strains fnrKO_C, galMKO_C and mapAKO_C.
| Bacterial strains | Challenge dose | Number of animals | Bacteraemiaa | Pb |
|---|---|---|---|---|
| MC58 wild type | 1.7 × 107 | 20 | 6.3 × 105 | |
| fnrKO_C | 1.5 × 107 | 10 | 2.7 × 106 | 0.23 |
| mapAKO_C | 1.5 × 107 | 10 | 2.3 × 106 | 0.23 |
| galMKO_C | 1.5 × 107 | 10 | 2.3 × 106 | 0.47 |
Values are geometric means of the bacterial cfu ml−1 measured in the blood of each animal.
The significance of difference in the level of bacteraemia was evaluated by two-tailed t-test.
Six-week-old BALB/c mice, 10 mice per group, were infected with the indicated amount of bacteria. Bacteraemia was measured 18 h after intraperitoneal challenge.