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. 2008 Mar;172(3):592–602. doi: 10.2353/ajpath.2008.070834

Figure 1.

Figure 1

Expression of CysLT1R and CysLT2R in mouse hearts. A: Quantitative real-time PCR was used to assess gene expression for the two CysLT receptors relative to GAPDH expression in ntg mouse hearts (n = 3) as described in the Materials and Methods section. Open bars, sham-operated mice; black bars, hearts 3 hours after I/R; gray bars, hearts 48 hours after I/R. *P < 0.05 compared to sham-operated controls. B: TTC-stained heart slice from a CysLT2R-deficient LacZ mouse 3 hours after I/R injury. C: Representative CysLT2R expression in boxed region of the slice shown in B detected via the reporter gene LacZ with blue X-gal staining. D: CysLT2R expression (via reporter LacZ/X-gal staining) in a heart slice from a CysLT2R-deficient LacZ mouse having undergone 48 hours of I/R. Similar patterns of expression were observed in two additional mice at 3 and 48 hours after I/R.