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P-gp activity in K562, HL60 and their variant resistant cell lines. P-gp activity was measured by the uptake of DiOC2(3) and rhodamine in either presence or absence of either zosuquidar (grey) or CsA (black). Two examples histograms K562 versus K562/Dox and HL60 versus HL60/DNR are presented in this figure.
