Table 2.

Hormone levels

Variable	Baseline	Oral TU	Placebo
Total testosterone (nmol/L)	9.4 ± 2	10.2 ± 3.9	10.4 ± 2.4
Free testosterone (nmol/L)	0.23 ± 0.06	0.27 ± 0.1	0.25 ± 0.06
(%)	2.3 ± 0.5	2.7 ± 0.4⁎	2.4 ± 0.4
Bioavailable testosterone (nmol/L)	5.2 ± 1.6	6.3 ± 2.5	5.6 ± 1.4
(%)	52 ± 12	62 ± 10⁎	54 ± 10
Dihydrotestosterone (nmol/L)	1.18 ± 0.33	2.2 ± 1⁎	1.1 ± 0.3
Sex hormone–binding globulin (nmol/L)	29 ± 17	18.6 ± 7.7⁎	25.3 ± 10.8
17β-Estradiol (pmol/L)	123 ± 75	141 ± 64	176 ± 102
Follicular-stimulating hormone (IU/L)	5.9 ± 2	4.2 ± 1.6⁎	5.8 ± 1.8
Luteinizing hormone (IU/L)	3.9 ± 2	2.1 ± 1.1⁎	3.8 ± 1.5

Values expressed as mean ± SD.

^⁎p <0.01 compared with placebo.