Table 3.

Metabolic and hemostatic variables

Variable	Baseline	Oral TU	Placebo
Total cholesterol (mmol/L)	4.3 ± 1.3	4.9 ± 1.5	5.2 ± 1.2
(mg/dl)	168 ± 51	191 ± 58	203 ± 47
High-density lipoprotein cholesterol (mmol/L)	0.99 ± 0.2	0.9 ± 0.3⁎	1.1 ± 0.2
(mg/dl)	40 ± 8	35 ± 12	43 ± 8
Low-density lipoprotein cholesterol (mmol/L)	2.5 ± 1	3.1 ± 1.5	3.1 ± 1.1
(mg/dl)	97 ± 39	120 ± 58	121 ± 43
High-density–low-density lipoprotein cholesterol ratio	4.37 ± 0.77	5.3 ± 1.3†	4.9 ± 1
Triglycerides (mmol/L)	1.68 ± 0.68	2.1 ± 1.7	2.1 ± 1
Lipoprotein(a) (mg/L)	Not done	276 ± 338	323 ± 362
Apolipoprotein A1 (g/L)	Not done	1.2 ± 0.3†	1.3 ± 0.2
Apolipoprotein B (g/L)	Not done	1 ± 0.2	1 ± 0.2
Apolipoprotein A:Apolipoprotein B	Not done	1.2 ± 0.2	1.3 ± 0.2
Glucose (mmol/L)	5.9 ± 1.3	5.9 ± 1	5.9 ± 0.9
Insulin (mU/L)	Not done	9.7 ± 4	10 ± 4
Plasminogen activator-1 (ng/ml)	92 ± 41	89 ± 39	92 ± 52
Fibrinogen (g/L)	3.4 ± 0.7	3.2 ± 0.7	3.2 ± 0.8
Factor VII (u/dl)	116 ± 28	105 ± 26	109 ± 25

Values expressed as mean ± SD.

^⁎p <0.001 compared with placebo.

^†p = 0.01 compared with placebo.