Table 1.
Expression patterns of Hoxd genes, Hoxb1 and Hoxb1/LacZ transposed at Hoxd during embryogenesis.
| Embryonic stage |
Wild type embryos |
Hoxb1/LacZ embryos |
||||
|---|---|---|---|---|---|---|
| Tissue | 3′ Hoxd (d1-d10) | 5′ Hoxd (d11-d13) | Hoxb1 | LacZ | Hoxd13 | |
| E7.5 | extra-embryonic; anterior yolk sac mesoderm |
− | − | − | − | − |
| primitive streak and adjacent embryonic mesoderm |
− | − | + | + | + | |
| E9.5 | rhombomere 1 and 2 | − | − | − | − | − |
| rhombomere 4 | − | − | + | − | − | |
| tail bud | + | + | + | + (extends anteriorly) |
+ (reinforced in posterior embryo) |
|
| limb and genital buds | + | − | − | ND | − | |
| E10.5 | rhombomere 1 and 2 | − | − | − | − | − |
| rhombomere 4 | − | − | + | − | − | |
| tail bud | + | + | + | + (extends anteriorly) |
+ | |
| limb and genital buds | + | + | − | + (distal part of the buds) |
+ | |
−, not expressed; +, expressed; ND, not determined