Table 1. Functional categories of Myc target genes as indicated by KEGG pathways.
KEGG_PATHWAY: Term | Count | % | PValue |
HSA04110: Cell Cycle | 25 | 1.73% | 9.67E-05 |
HSA03010: Ribosome | 40 | 2.77% | 1.18E-04 |
HSA00190: Oxidative Phosphorylation | 27 | 1.87% | 5.53E-04 |
HSA00251: Glutamate Metabolism | 10 | 0.69% | 1.28E-03 |
HSA03030: DNA Polymerase | 9 | 0.62% | 1.49E-03 |
HSA00230: Purine Metabolism | 27 | 1.87% | 4.02E-03 |
HSA00970: Aminoacyl-tRNA Synthetases | 9 | 0.62% | 8.07E-03 |
HSA03060: Protein Export | 6 | 0.42% | 9.85E-03 |
HSA00351: 1,1,1-Trichloro-2,2-Bis(4-Chlorophenyl)Ethane (DDT) Degradation | 3 | 0.21% | 2.50E-02 |
HSA00630: Glyoxylate And Dicarboxylate Metabolism | 5 | 0.35% | 2.80E-02 |
HSA00440: Aminophosphonate Metabolism | 6 | 0.42% | 4.17E-02 |
HSA00350: Tyrosine Metabolism | 11 | 0.76% | 5.19E-02 |
HSA00626: Nitrobenzene Degradation | 5 | 0.35% | 5.70E-02 |
HSA00240: Pyrimidine Metabolism | 15 | 1.04% | 6.92E-02 |
HSA00193: ATP Synthesis | 9 | 0.62% | 7.75E-02 |
HSA00400: Phenylalanine, Tyrosine And Tryptophan Biosynthesis | 4 | 0.28% | 7.76E-02 |
1440 of the 1469 Myc targets were analyzed using the ‘Functional Annotation Tool’ in DAVID (http://david.abcc.ncifcrf.gov/).