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. 2008 Mar 12;3(3):e1798. doi: 10.1371/journal.pone.0001798

Table 1. Functional categories of Myc target genes as indicated by KEGG pathways.

KEGG_PATHWAY: Term Count % PValue
HSA04110: Cell Cycle 25 1.73% 9.67E-05
HSA03010: Ribosome 40 2.77% 1.18E-04
HSA00190: Oxidative Phosphorylation 27 1.87% 5.53E-04
HSA00251: Glutamate Metabolism 10 0.69% 1.28E-03
HSA03030: DNA Polymerase 9 0.62% 1.49E-03
HSA00230: Purine Metabolism 27 1.87% 4.02E-03
HSA00970: Aminoacyl-tRNA Synthetases 9 0.62% 8.07E-03
HSA03060: Protein Export 6 0.42% 9.85E-03
HSA00351: 1,1,1-Trichloro-2,2-Bis(4-Chlorophenyl)Ethane (DDT) Degradation 3 0.21% 2.50E-02
HSA00630: Glyoxylate And Dicarboxylate Metabolism 5 0.35% 2.80E-02
HSA00440: Aminophosphonate Metabolism 6 0.42% 4.17E-02
HSA00350: Tyrosine Metabolism 11 0.76% 5.19E-02
HSA00626: Nitrobenzene Degradation 5 0.35% 5.70E-02
HSA00240: Pyrimidine Metabolism 15 1.04% 6.92E-02
HSA00193: ATP Synthesis 9 0.62% 7.75E-02
HSA00400: Phenylalanine, Tyrosine And Tryptophan Biosynthesis 4 0.28% 7.76E-02

1440 of the 1469 Myc targets were analyzed using the ‘Functional Annotation Tool’ in DAVID (http://david.abcc.ncifcrf.gov/).