Effects of chronic administration of beta-blockers on cell count and eosinophils in bronchoalveolar lavage (BAL) of antigen-sentized and -challenged BALB/cJ mice. (A) Total cell count and (B) eosinophil numbers in BAL from saline-challenged mice (CONTROL), antigen-challenged mice (S/C) administered vehicle, the selective beta2-adrenoceptor antagonist ICI 118,551 for 28 days (ICI 28 d), or the nonselective beta-adrenoceptor antagonist nadolol for 28 days (Nad 28 d) (Figure 1, protocol 1). BAL was collected 24 hours after the last challenge. Values are the means ± SEM of data from 6 to 12 mice in each group (n = 6–12). #P < 0.05, significantly different compared with saline-challenged mice; *P < 0.05, significantly different compared with antigen-challenged mice.