Figure 3.

Effects of chronic administration of nadolol on cytokines levels in the BAL of BALB/cJ mice. The concentration of IL-13, IL-10, IL-5, TGF-β1, and RANTES was measured by multiplex enzyme-linked immunosorbent assay analysis of BAL harvested 24 hours after the last challenge from saline-challenged mice (CONTROL), antigen-challenged mice (S/C) administered vehicle or nadolol for 28 days (Nad 28 d) (Figure 1, protocol 2). Values are the means ± SEM of data from seven to eight mice in each group (n = 7–8). ^#P < 0.05, significantly different compared with saline-challenged mice; *P < 0.05, significantly different compared with antigen-challenged mice.