TABLE 2.
Overall in vitro sensitivity for each drug according to the species tested
| Drug |
P. vivax
|
P. falciparum
|
||
|---|---|---|---|---|
| No. of acceptable assays/ total no. of assays harvested (%)a | Geometric mean IC50 value (nM) (95% CI) | No. of acceptable assays/total no. of assays harvested (%) | Geometric mean IC50 value (nM) (95% CI) | |
| Chloroquine | 155/170 (91.2) | 295 (227-384) | 170/221 (77) | 47.4 (42.2-53.3) |
| Amodiaquine | 143/144 (99.3) | 15.4 (12.7-18.7) | 120/137 (88) | 5.59 (4.96-6.29) |
| Artesunate | 136/149 (91.3) | 1.31 (1.07-1.59) | 127/157 (81) | 0.64 (0.53-0.79) |
| Lumefantrine | 54/64 (83) | 19.3 (13.2-28.0) | 101/124 (82) | 10.2 (7.6-13.9) |
| Mefloquine | 108/108 (100) | 12.7 (10.3-15.5) | 146/166 (88) | 8.5 (6.98-10.4) |
| Piperaquine | 125/137 (91.2) | 21.9 (18.5-25.8) | 165/200 (83) | 14.5 (13.2-16.1) |
a
Values shown are the total number of assays with acceptable IC50 values/number of assays harvested.